A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors

Understanding the cellular constituents of the prostate is essential for identifying the cell of origin for prostate adenocarcinoma. Here, we describe a comprehensive single-cell atlas of the adult mouse prostate epithelium, which displays extensive heterogeneity. We observe distal lobe-specific lum...

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Bibliographic Details
Main Authors: Laura Crowley, Francesco Cambuli, Luis Aparicio, Maho Shibata, Brian D Robinson, Shouhong Xuan, Weiping Li, Hanina Hibshoosh, Massimo Loda, Raul Rabadan, Michael M Shen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
epithelial heterogeneity
multipotent progenitor
organoids
renal grafts
Online Access:https://elifesciences.org/articles/59465

Internet

https://elifesciences.org/articles/59465

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