Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis.

<h4>Purpose</h4>Chronic Hepatitis C Virus (HCV)-infected patients with liver cirrhosis (LC) respond poorly to interferon-alpha (IFN-α) and ribavirin (RBV) combination therapy, but the reason for this is unclear. We previously reported that HCV-infection induces endoplasmic reticulum (ER)...

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Main Authors: Partha K Chandra, Feyza Gunduz, Sidhartha Hazari, Ramazan Kurt, Rajesh Panigrahi, Bret Poat, David Bruce, Ari J Cohen, Humberto E Bohorquez, Ian Carmody, George Loss, Luis A Balart, Tong Wu, Srikanta Dash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108616

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https://doi.org/10.1371/journal.pone.0108616

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