Pharmacokinetics of Intravitreal Anti-VEGF Drugs in Age-Related Macular Degeneration

Pharmacokinetics of Intravitreal Anti-VEGF Drugs in Age-Related Macular Degeneration

Intravitreal administration of anti-vascular endothelial growth factor (VEGF) antibodies has become the standard treatment for Age-Related Macular Degeneration; however, the knowledge of their pharmacokinetics is limited. A comprehensive review of the preclinical and clinical pharmacokinetic data th...

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Bibliographic Details
Main Authors: Laura García-Quintanilla, Andrea Luaces-Rodríguez, María Gil-Martínez, Cristina Mondelo-García, Olalla Maroñas, Víctor Mangas-Sanjuan, Miguel González-Barcia, Irene Zarra-Ferro, Pablo Aguiar, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
vascular endothelial growth factor/antagonists &amp
inhibitors
ranibizumab
aflibercept
bevacizumab
Age-Related Macular Degeneration
pharmacokinetics
intravitreal
Online Access:https://www.mdpi.com/1999-4923/11/8/365

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https://www.mdpi.com/1999-4923/11/8/365

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