Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh
Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/37291 |