Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh

Many secondary active membrane transporters pump substrates against concentration gradients by coupling their uptake to symport of sodium ions. Symport requires the substrate and ions to be always transported together. Cooperative binding of the solutes is a key mechanism contributing to coupled tra...

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Bibliographic Details
Main Authors: SeCheol Oh, Olga Boudker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/37291