Modelling the Activation Pathways in Full-Length Src Kinase

Src kinases play fundamental roles in several crucial cell processes. Their activity is tightly regulated by conformational transitions between the active and the inactive forms, which are carried out by complex protein structural rearrangements. Here, we present an in-depth study of such structural...

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Bibliographic Details
Main Authors: Josephine Alba, Maria Montagna, Marco D’Abramo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biophysica
Subjects:
Online Access:https://www.mdpi.com/2673-4125/1/2/18