Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy

Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy

Pregnant women have been carefully observed during the COVID-19 pandemic, as the pregnancy-specific immune adaptation is known to increase the risk for infections. Recent evidence indicates that even though most pregnant have a mild or asymptomatic course, a severe course of COVID-19 and a higher ri...

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Bibliographic Details
Main Authors: Ann-Christin Tallarek, Christopher Urbschat, Luis Fonseca Brito, Stephanie Stanelle-Bertram, Susanne Krasemann, Giada Frascaroli, Kristin Thiele, Agnes Wieczorek, Nadine Felber, Marc Lütgehetmann, Udo R. Markert, Kurt Hecher, Wolfram Brune, Felix Stahl, Gülsah Gabriel, Anke Diemert, Petra Clara Arck
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
prenatal infection
vertical transfer
variants of concern
SARS-CoV
T cell response
human trial
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.698578/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.698578/full

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