Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood.

Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood.

RATIONALE: Due to the invasive nature of the procedures involved, most studies of Mycobacterium tuberculosis (Mtb)-specific immunity in humans have focused on the periphery rather than the site of active infection, the lung. Recently, antigens associated with Mtb-latency and -dormancy have been desc...

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Bibliographic Details
Main Authors: Teresa Chiacchio, Elisa Petruccioli, Valentina Vanini, Ornella Butera, Gilda Cuzzi, Linda Petrone, Giuseppe Matteucci, Francesco Nicola Lauria, Kees L M C Franken, Enrico Girardi, Tom H M Ottenhoff, Delia Goletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3213161?pdf=render

Internet

http://europepmc.org/articles/PMC3213161?pdf=render

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