Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses

Fibroproliferative disorders occur in both humans and horses following skin injury. In horses, wound healing on the limb is often complicated by the formation of fibroproliferative exuberant granulation tissue, characterized by persistent expression of pro-fibrotic transforming growth factor-beta1 (...

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Bibliographic Details
Main Authors: Lyn M. Wise, Gabriella S. Stuart, Kevalee Sriutaisuk, Brooke R. Adams, Christopher B. Riley, Christine L. Theoret
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fvets.2020.577835/full