MACC1 Contributes to the Development of Osteosarcoma Through Regulation of the HGF/c-Met Pathway and Microtubule Stability

MACC1 Contributes to the Development of Osteosarcoma Through Regulation of the HGF/c-Met Pathway and Microtubule Stability

Osteosarcoma (OS) is the most prevalent human bone malignancy, and presents a global annual morbidity of approximately five cases per million. Notably, precise and efficient targeted therapy has become the most promising strategy for the treatment of OS; however, there is still an urgent need for th...

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Bibliographic Details
Main Authors: Jia Wen, Yi Xie, Yingqiang Zhang, Jiazhen Li, Jiaping Li, Yan Zhang, Xinchang Lu, Yi Zhang, Yongkui Liu, Tao Liu, Longqing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MACC1
osteosarcoma
HGF/c-Met
proliferation
angiogenesis
microtubule stability
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.00825/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.00825/full

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