Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study [version 1; referees: 2 approved]

Background: Although nausea and vomiting are very common in pregnancy, their pathogenesis is poorly understood. We tested the hypothesis that circulating growth and differentiation factor 15 (GDF15) concentrations in early pregnancy, whose gene is implicated in hyperemesis gravidarum, are associated...

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Main Authors: Clive J. Petry, Ken K. Ong, Keith A. Burling, Peter Barker, Sandra F. Goodburn, John R.B. Perry, Carlo L. Acerini, Ieuan A. Hughes, Rebecca C. Painter, Gijs B. Afink, David B. Dunger, Stephen O'Rahilly
Format: Article
Language:English
Published: Wellcome 2018-09-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/3-123/v1