The Collagen V Homotrimer [α1(V)]3 Production Is Unexpectedly Favored over the Heterotrimer [α1(V)]2α2(V) in Recombinant Expression Systems

Collagen V, a fibrillar collagen with important functions in tissues, assembles into distinct chain associations. The most abundant and ubiquitous molecular form is the heterotrimer [α1(V)]2α2(V). In the attempt to produce high levels of recombinant collagen V heterotrimer for biomedical device uses...

Full description

Bibliographic Details
Main Authors: Muriel Roulet, Merja Välkkilä, Hélène Chanut-Delalande, Eija-Riitta Hämäläinen, Efrat Kessler, Leena Ala-Kokko, Minna Männikkö, Christelle Bonod-Bidaud, Florence Ruggiero
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/376927