Distinct virulence of Rift Valley fever phlebovirus strains from different genetic lineages in a mouse model.

Rift Valley fever phlebovirus (RVFV) causes high rates of abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or blindness in humans. Viral transmission occurs via mosquito vectors in endemic areas, which necessitates regular vaccination of susceptible livestock anim...

Full description

Bibliographic Details
Main Authors: Tetsuro Ikegami, Aaron Balogh, Shoko Nishiyama, Nandadeva Lokugamage, Tais B Saito, John C Morrill, Vinay Shivanna, Sabarish V Indran, Lihong Zhang, Jennifer K Smith, David Perez, Terry L Juelich, Igor Morozov, William C Wilson, Alexander N Freiberg, Juergen A Richt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5739399?pdf=render