Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer.

BACKGROUND: Genomic instability with frequent DNA copy number alterations is one of the key hallmarks of carcinogenesis. The chromosomal regions with frequent DNA copy number gain and loss in human gastric cancer are still poorly defined. It remains unknown how the DNA copy number variations contrib...

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Bibliographic Details
Main Authors: Biao Fan, Somkid Dachrut, Ho Coral, Siu Tsan Yuen, Kent Man Chu, Simon Law, Lianhai Zhang, Jiafu Ji, Suet Yi Leung, Xin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335165?pdf=render