Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development.

OBJECTIVES:In congenital heart malformations with pulmonary stenosis to atresia an abnormal lateral ductus arteriosus to left pulmonary artery connection can lead to a localised narrowing (pulmonary ductal coarctation) or even interruption We investigated embryonic remodelling and pathogenesis of th...

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Main Authors: Adriana C Gittenberger-de Groot, Joshua C Peterson, Lambertus J Wisse, Arno A W Roest, Robert E Poelmann, Regina Bökenkamp, Nynke J Elzenga, Mark Hazekamp, Margot M Bartelings, Monique R M Jongbloed, Marco C DeRuiter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228478