USP14 maintains HIF1-α stabilization via its deubiquitination activity in hepatocellular carcinoma
Abstract Hepatocellular carcinoma (HCC) is the most common visceral neoplasms with its heterogeneity and high rate of recurrence. HCC is characterized to be delayed diagnosis and the development of resistant disease. However, the molecular mechanism for HCC pathogenesis and progression remains large...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-08-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04089-6 |