An integrative assessment to determine the genotoxic hazard of estuarine sediments: combining cell and whole-organism responses

An integrative assessment to determine the genotoxic hazard of estuarine sediments: combining cell and whole-organism responses

The application of the Comet assay in environmental monitoring remains challenging in face of the complexity of environmental stressors, e.g. when dealing with estuarine sediments, that hampers the drawing of cause-effect relationships. Although the in vitro Comet assay may circumvent confounding fa...

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Bibliographic Details
Main Authors: Pedro M. Costa, Miguel ePinto, Ana Margarida Vicente, Cátia eGonçalves, Ana P. Rodrigo, Henriqueta eLouro, Maria H. Costa, Sandra eCaeiro, Maria João Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Genetics
Subjects:
Comet Assay
Oxidative Stress
Environmental Risk Assessment
HepG2 cells
Sediment contamination
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00437/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00437/full

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