Aurora kinase inhibitors: which role in the treatment of chronic myelogenous leukemia patients resistant to imatinib?

<p>At present, there are no compounds in clinical development in the field of chronic myeloid leukemia (CML) or Philadelphia-positive (Ph+) acute lymphoblastic leukemia (ALL) that have been documented to harbor significant activity against the imatinib-resistant T315I mutation. Recent reports...

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Bibliographic Details
Main Authors: Giovanni Martinelli, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Daniela Cilloni, Michele Baccarani
Format: Article
Language:English
Published: PAGEPress Publications 2009-02-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/5