Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations.

Multiple sclerosis risk variant HLA-DRB1*1501 associates with high expression of DRB1 gene in different human populations.

The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen presentation as the pathogenic mechanism though this does not fully explain the disease association. The identification of exp...

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Bibliographic Details
Main Authors: Antonio Alcina, María Del Mar Abad-Grau, María Fedetz, Guillermo Izquierdo, Miguel Lucas, Oscar Fernández, Dorothy Ndagire, Antonio Catalá-Rabasa, Agustín Ruiz, Javier Gayán, Concepción Delgado, Carmen Arnal, Fuencisla Matesanz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3258250?pdf=render

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http://europepmc.org/articles/PMC3258250?pdf=render

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