Flavaglines alleviate doxorubicin cardiotoxicity: implication of Hsp27.

<h4>Background</h4>Despite its effectiveness in the treatment of various cancers, the use of doxorubicin is limited by a potentially fatal cardiomyopathy. Prevention of this cardiotoxicity remains a critical issue in clinical oncology. We hypothesized that flavaglines, a family of natura...

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Bibliographic Details
Main Authors: Yohann Bernard, Nigel Ribeiro, Frédéric Thuaud, Gülen Türkeri, Ronan Dirr, Mounia Boulberdaa, Canan G Nebigil, Laurent Désaubry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22065986/pdf/?tool=EBI