Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals.

Recent advances in epigenomics have made it possible to map genome-wide regulatory regions using empirical methods. Subsequent comparative epigenomic studies have revealed that regulatory regions diverge rapidly between genome of different species, and that the divergence is more pronounced in enhan...

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Bibliographic Details
Main Authors: Iksoo Huh, Isabel Mendizabal, Taesung Park, Soojin V Yi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6192654?pdf=render