MPRAnalyze: statistical framework for massively parallel reporter assays

MPRAnalyze: statistical framework for massively parallel reporter assays

Abstract Massively parallel reporter assays (MPRAs) can measure the regulatory function of thousands of DNA sequences in a single experiment. Despite growing popularity, MPRA studies are limited by a lack of a unified framework for analyzing the resulting data. Here we present MPRAnalyze: a statisti...

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Bibliographic Details
Main Authors: Tal Ashuach, David S. Fischer, Anat Kreimer, Nadav Ahituv, Fabian J. Theis, Nir Yosef
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1787-z

Internet

http://link.springer.com/article/10.1186/s13059-019-1787-z

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