Primary Chicken and Duck Endothelial Cells Display a Differential Response to Infection with Highly Pathogenic Avian Influenza Virus

Primary Chicken and Duck Endothelial Cells Display a Differential Response to Infection with Highly Pathogenic Avian Influenza Virus

Highly pathogenic avian influenza viruses (HPAIVs) in gallinaceous poultry are associated with viral infection of the endothelium, the induction of a ‘cytokine storm, and severe disease. In contrast, in Pekin ducks, HPAIVs are rarely endothelial tropic, and a cytokine storm is not observed. To date,...

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Bibliographic Details
Main Authors: Zhen Wei Marcus Tong, Anjana C. Karawita, Colin Kern, Huaijun Zhou, Jane E. Sinclair, Limin Yan, Keng Yih Chew, Sue Lowther, Lee Trinidad, Arjun Challagulla, Karel A. Schat, Michelle L. Baker, Kirsty R. Short
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
avian influenza
endothelial cells
chicken
duck
cytokine storm
H5N1
Online Access:https://www.mdpi.com/2073-4425/12/6/901

Internet

https://www.mdpi.com/2073-4425/12/6/901

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