Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies

Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies

Calcific aortic valve disease (CAVD) is the most frequent heart valve disorder. It is characterized by an active remodeling process accompanied with valve mineralization, that results in a progressive aortic valve narrowing, significant restriction of the valvular area, and impairment of blood flow....

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Bibliographic Details
Main Authors: Brunilda Alushi, Lavinia Curini, Mary Roxana Christopher, Herko Grubitzch, Ulf Landmesser, Amedeo Amedei, Alexander Lauten
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
severe aortic stenosis
calcific aortic valve
aortic valve replacement
TAVR
microbiome
immune system
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00685/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00685/full

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