simATAC: a single-cell ATAC-seq simulation framework

Abstract Single-cell assay for transposase-accessible chromatin sequencing (scATAC-seq) identifies regulated chromatin accessibility modules at the single-cell resolution. Robust evaluation is critical to the development of scATAC-seq pipelines, which calls for reproducible datasets for benchmarking...

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Bibliographic Details
Main Authors: Zeinab Navidi, Lin Zhang, Bo Wang
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02270-w