Zero Echo Time <sup>17</sup>O-MRI Reveals Decreased Cerebral Metabolic Rate of Oxygen Consumption in a Murine Model of Amyloidosis

Zero Echo Time <sup>17</sup>O-MRI Reveals Decreased Cerebral Metabolic Rate of Oxygen Consumption in a Murine Model of Amyloidosis

The cerebral metabolic rate of oxygen consumption (CMRO<sub>2</sub>) is a key metric to investigate the mechanisms involved in neurodegeneration in animal models and evaluate potential new therapies. CMRO<sub>2 </sub>can be measured by direct <sup>17</sup>O magnet...

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Bibliographic Details
Main Authors: Celine Baligand, Olivier Barret, Amélie Tourais, Jean-Baptiste Pérot, Didier Thenadey, Fanny Petit, Géraldine Liot, Marie-Claude Gaillard, Julien Flament, Marc Dhenain, Julien Valette
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
cerebral metabolic rate of oxygen
magnetic resonance imaging
oxygen-17
zero echo time
APP/PS1
Alzheimer’s disease
Online Access:https://www.mdpi.com/2218-1989/11/5/263

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https://www.mdpi.com/2218-1989/11/5/263

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