Accelerated Sensitivity Analysis in High-Dimensional Stochastic Reaction Networks.

Existing sensitivity analysis approaches are not able to handle efficiently stochastic reaction networks with a large number of parameters and species, which are typical in the modeling and simulation of complex biochemical phenomena. In this paper, a two-step strategy for parametric sensitivity ana...

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Bibliographic Details
Main Authors: Georgios Arampatzis, Markos A Katsoulakis, Yannis Pantazis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4498611?pdf=render