The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells

Abstract Background Cancer cachexia is a cancer-induced metabolic disorder and a major cause of cancer-induced death. The constituents of cancer cachexia include an increase in energy expenditure, hepatic gluconeogenesis, fat lipolysis, and skeletal-muscle proteolysis and a decrease in body weight....

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Bibliographic Details
Main Authors: Feng Wang, Hongyi Liu, Lijuan Hu, Yunfei Liu, Yijie Duan, Rui Cui, Wencong Tian
Format: Article
Language:English
Published: BMC 2018-04-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4271-3