Simultaneous PET/fMRI Detects Distinctive Alterations in Functional Connectivity and Glucose Metabolism of Precuneus Subregions in Alzheimer’s Disease

Simultaneous PET/fMRI Detects Distinctive Alterations in Functional Connectivity and Glucose Metabolism of Precuneus Subregions in Alzheimer’s Disease

As a central hub in the interconnected brain network, the precuneus has been reported showing disrupted functional connectivity and hypometabolism in Alzheimer’s disease (AD). However, as a highly heterogeneous cortical structure, little is known whether individual subregion of the precuneus is unif...

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Bibliographic Details
Main Authors: Miao Zhang, Wanqing Sun, Ziyun Guan, Jialin Hu, Binyin Li, Guanyu Ye, Hongping Meng, Xinyun Huang, Xiaozhu Lin, Jin Wang, Jun Liu, Biao Li, Yaoyu Zhang, Yao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
mild cognitive impairment
hybrid PET/MRI
glucose metabolism
functional connectivity
precuneus
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.737002/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.737002/full

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