Ex-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapy.

Ex-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapy.

Three-dimensional (3-D) culture models are emerging as invaluable tools in tumor biology, since they reproduce tissue-specific structural features and cell-cell interactions more accurately than conventional 2-D cultures. Multiple Myeloma, which depends on myeloma cell-Bone Marrow microenvironment i...

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Bibliographic Details
Main Authors: Marina Ferrarini, Nathalie Steimberg, Maurilio Ponzoni, Daniela Belloni, Angiola Berenzi, Stefania Girlanda, Federico Caligaris-Cappio, Giovanna Mazzoleni, Elisabetta Ferrero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23990965/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23990965/?tool=EBI

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