Iron regulates myeloma cell/macrophage interaction and drives resistance to bortezomib

Iron regulates myeloma cell/macrophage interaction and drives resistance to bortezomib

Iron plays a major role in multiple processes involved in cell homeostasis such as metabolism, respiration and DNA synthesis. Cancer cells exhibit pronounced iron retention as compared to healthy counterpart. This phenomenon also occurs in multiple myeloma (MM), a hematological malignancy characteri...

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Bibliographic Details
Main Authors: Giuseppina Camiolo, Alessandro Barbato, Cesarina Giallongo, Nunzio Vicario, Alessandra Romano, Nunziatina L. Parrinello, Rosalba Parenti, Joaquín Cantón Sandoval, Diana García-Moreno, Giacomo Lazzarino, Roberto Avola, Giuseppe A. Palumbo, Victoriano Mulero, Giovanni Li Volti, Daniele Tibullo, Francesco Di Raimondo
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Redox Biology
Subjects:
Iron
Multiple myeloma
Zebrafish
Monocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308168

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http://www.sciencedirect.com/science/article/pii/S2213231720308168

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