Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory

Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhanced spine turnover has enhanced learning.

Bibliographic Details
Main Authors: Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Tawnie K. Silva, Elaine Lu, Ximiao Wen, Panayiota Poirazi, Joshua T. Trachtenberg, Alcino J. Silva
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02751-2

Internet

https://doi.org/10.1038/s41467-017-02751-2

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