Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy.

A metabolome-wide genome-wide association study (mGWAS) aims to discover the effects of genetic variants on metabolome phenotypes. Most mGWASes use as phenotypes concentrations of limited sets of metabolites that can be identified and quantified from spectral information. In contrast, in an untarget...

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Bibliographic Details
Main Authors: Rico Rueedi, Roger Mallol, Johannes Raffler, David Lamparter, Nele Friedrich, Peter Vollenweider, Gérard Waeber, Gabi Kastenmüller, Zoltán Kutalik, Sven Bergmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5711027?pdf=render