PDXGEM: patient-derived tumor xenograft-based gene expression model for predicting clinical response to anticancer therapy in cancer patients

Abstract Background Cancer is a highly heterogeneous disease with varying responses to anti-cancer drugs. Although several attempts have been made to predict the anti-cancer therapeutic responses, there remains a great need to develop highly accurate prediction models of response to the anti-cancer...

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Bibliographic Details
Main Authors: Youngchul Kim, Daewon Kim, Biwei Cao, Rodrigo Carvajal, Minjung Kim
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Bioinformatics
Subjects:
PDX
Online Access:http://link.springer.com/article/10.1186/s12859-020-03633-z