Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease.

Brain mitochondrial dysfunction is hallmark pathology of Alzheimer's disease (AD). Recently, the role of synaptosomal mitochondrial dysfunction in the development of synaptic injury in AD has received increasing attention. Synaptosomal mitochondria are a subgroup of neuronal mitochondria specif...

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Bibliographic Details
Main Authors: Lu Wang, Lan Guo, Lin Lu, Huili Sun, Muming Shao, Simon J Beck, Lin Li, Janani Ramachandran, Yifeng Du, Heng Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4778903?pdf=render