Spontaneous Ca2+ Influx in Drosophila Pupal Neurons Is Modulated by IP3-Receptor Function and Influences Maturation of the Flight Circuit

Inositol 1,4,5-trisphosphate receptors (IP3R) are Ca2+ channels on the neuronal endoplasmic reticulum (ER) membrane. They are gated by IP3, produced upon external stimulation and activation of G protein-coupled receptors on the plasma membrane (PM). IP3-mediated Ca2+ release, and the resulting deple...

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Bibliographic Details
Main Authors: Sumita Chakraborty, Gaiti Hasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Trp
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00111/full