Mechanisms of NOS1AP action on NMDA receptor-nNOS signalling

NMDA receptors (NMDAR) are glutamate-gated calcium channels that play pivotal roles in fun-damental aspects of neuronal function. Dysregulated receptor function contributes to many disor-ders. Recruitment by NMDARs of calcium-dependent enzyme nNOS via PSD95 is seen as a key contributor to neuronal d...

Full description

Bibliographic Details
Main Authors: Michael James Courtney, Li-Li eLi, Yvonne Y Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00252/full