Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy

Influence of low-dose radiation on abscopal responses in patients receiving high-dose radiation and immunotherapy

Abstract Background Preclinical evidence suggests that low-dose radiation may overcome the inhibitory effects of the tumor stroma and improve a tumor’s response to immunotherapy, when combined with high-dose radiation to another tumor. The aim of this study was to evaluate tumor responses to this co...

Full description

Bibliographic Details
Main Authors: Hari Menon, Dawei Chen, Rishab Ramapriyan, Vivek Verma, Hampartsoum B. Barsoumian, Taylor R. Cushman, Ahmed I. Younes, Maria A. Cortez, Jeremy J. Erasmus, Patricia de Groot, Brett W. Carter, David S. Hong, Isabella C. Glitza, Renata Ferrarotto, Mehmet Altan, Adi Diab, Stephen G. Chun, John V. Heymach, Chad Tang, Quynh N. Nguyen, James W. Welsh
Format: Article
Language:English
Published: BMJ Publishing Group 2019-09-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Stereotactic ablative radiation therapy
Low-dose radiotherapy
Immunotherapy
Abscopal effect
Metastatic cancer
Online Access:http://link.springer.com/article/10.1186/s40425-019-0718-6

Internet

http://link.springer.com/article/10.1186/s40425-019-0718-6

Similar Items