Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects

Antipsychotic Drug Responsiveness and Dopamine Receptor Signaling; Old Players and New Prospects

Antipsychotic drugs targeting dopamine neurotransmission are still the principal mean of therapeutic intervention for schizophrenia. However, about one third of people do not respond to dopaminergic antipsychotics. Genome wide association studies (GWAS), have shown that multiple genetic factors play...

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Bibliographic Details
Main Authors: Antonio Rampino, Aleksandra Marakhovskaia, Tiago Soares-Silva, Silvia Torretta, Federica Veneziani, Jean Martin Beaulieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Psychiatry
Subjects:
dopamine
risk factors
antipsychotic agents
genetic variants
schizophrenia therapy
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00702/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00702/full

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