Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats

Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats

Background: Accumulating evidences indicate that the apoptosis of proximal tubular epithelial cells (PTECs) play a vital role in the progression of the diabetic kidney disease (DKD). This study aimed to explore the therapeutic potential of salidroside (SAL) in DKD and its underlying mechanism in ant...

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Bibliographic Details
Main Authors: Congcong Guo, Yun Li, Rui Zhang, Yaqin Zhang, Junyu Zhao, Jinming Yao, Jie Sun, Jianjun Dong, Lin Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
diabetic kidney disease
salidroside
apoptosis
BIM protein
proximal renal tubular epithelial cell
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01433/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01433/full

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