Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans.

The inflammatory component of non-alcoholic steatohepatitis (NASH) can lead to irreversible liver damage. Therefore there is an urgent need to identify novel interventions to combat hepatic inflammation. In mice, omitting cholesterol from the diet reduced hepatic inflammation. Considering the effect...

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Bibliographic Details
Main Authors: Jogchum Plat, Tim Hendrikx, Veerle Bieghs, Mike L J Jeurissen, Sofie M A Walenbergh, Patrick J van Gorp, Els De Smet, Maurice Konings, Anita C E Vreugdenhil, Yasmin Dias Guichot, Sander S Rensen, Wim A Buurman, Jan Willem M Greve, Dieter Lütjohann, Ronald P Mensink, Ronit Shiri-Sverdlov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4214692?pdf=render