Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroids

Abstract Background Uterine Fibroids (UFs) growth is ovarian steroid-dependent. Previous studies have shown that estrogen and progesterone play an important role in UF development. However, the mechanism underlying progesterone induced UF pathogenesis is largely unknown. In this study, we determined...

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Bibliographic Details
Main Authors: Mona Omar, Archana Laknaur, Ayman Al-Hendy, Qiwei Yang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Women's Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12905-019-0795-1