Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions

Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions

Parkinson's disease (PD) is defined by motor symptoms such as tremor at rest, bradykinesia, postural instability, and stiffness. In addition to the classical motor defects that define PD, up to 80% of patients experience cognitive changes and psychiatric disturbances, referred to as PD dementia...

Full description

Bibliographic Details
Main Authors: Lindsay E. Stoyka, Andrew E. Arrant, Drake R. Thrasher, Dreson L. Russell, Jennifer Freire, Casey L. Mahoney, Ashwin Narayanan, Aseel G. Dib, David G. Standaert, Laura A. Volpicelli-Daley
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Neurobiology of Disease
Subjects:
Dementia with Lewy Bodies
Parkinson's disease dementia
Alpha-synuclein
Fear conditioning
Social dominance
Fibrils
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119303833

Internet

http://www.sciencedirect.com/science/article/pii/S0969996119303833

Similar Items