The Membrane Glycoprotein M6a Endocytic/Recycling Pathway Involves Clathrin-Mediated Endocytosis and Affects Neuronal Synapses

The Membrane Glycoprotein M6a Endocytic/Recycling Pathway Involves Clathrin-Mediated Endocytosis and Affects Neuronal Synapses

Single point mutations or variations in the expression of the gene encoding the neuronal glycoprotein M6a have been associated with psychiatric disorders such as Alzheimer’s disease, depression and schizophrenia. In cultured neurons, M6a positively contributes to neurite extension, axon guidance, fi...

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Bibliographic Details
Main Authors: Micaela D. Garcia, Karina Formoso, Gabriela I. Aparicio, Alberto C. C. Frasch, Camila Scorticati
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
PLP protein family
neuronal plasticity
traffic
endosomal compartments
Rab GTPases
glycoprotein M6a
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00296/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00296/full

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