Genetic variants in microRNA machinery genes are associated [corrected] with idiopathic recurrent pregnancy loss risk.

OBJECTIVE: Key molecules involved in microRNA (miRNA) biogenesis, such as DROSHA, XPO5, and DICER, have been identified in trophoblast cells, confirming that the miRNA biogenesis pathway is active in human placenta. In addition, miRNAs regulate uterine gene expression associated with inflammatory re...

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Bibliographic Details
Main Authors: Yong Wook Jung, Young Joo Jeon, HyungChul Rah, Ji Hyang Kim, Ji Eun Shin, Dong Hee Choi, Sun Hee Cha, Nam Keun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4000197?pdf=render