Endocrine Resistance in Hormone Receptor Positive Breast Cancer–From Mechanism to Therapy

The importance and role of the estrogen receptor (ER) pathway has been well-documented in both breast cancer (BC) development and progression. The treatment of choice in women with metastatic breast cancer (MBC) is classically divided into a variety of endocrine therapies, 3 of the most common being...

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Bibliographic Details
Main Authors: Aradhana Rani, Justin Stebbing, Georgios Giamas, John Murphy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00245/full