Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development

The study of antigenic targets of naturally-acquired immunity is essential to identify and prioritize antigens for further functional characterization. We measured total IgG antibodies to 38 P. vivax antigens, investigating their relationship with prospective risk of malaria in a cohort of 1–3 years...

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Bibliographic Details
Main Authors: Camila Tenorio França, Michael T White, Wen-Qiang He, Jessica B Hostetler, Jessica Brewster, Gabriel Frato, Indu Malhotra, Jakub Gruszczyk, Christele Huon, Enmoore Lin, Benson Kiniboro, Anjali Yadava, Peter Siba, Mary R Galinski, Julie Healer, Chetan Chitnis, Alan F Cowman, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, Rick M Fairhurst, Julian C Rayner, Christopher L King, Ivo Mueller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Plasmodium vivax
IgG antibody
vaccine
clinical malaria
protection
natural immunity
Online Access:https://elifesciences.org/articles/28673

Internet

https://elifesciences.org/articles/28673

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