Uncovering and characterizing splice variants associated with survival in lung cancer patients.

Splice variants have been shown to play an important role in tumor initiation and progression and can serve as novel cancer biomarkers. However, the clinical importance of individual splice variants and the mechanisms by which they can perturb cellular functions are still poorly understood. To addre...

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Bibliographic Details
Main Authors: Sean West, Sushil Kumar, Surinder K Batra, Hesham Ali, Dario Ghersi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007469