Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging

Terminally Differentiated CD4+ T Cells Promote Myocardial Inflammaging

The cardiovascular and immune systems undergo profound and intertwined alterations with aging. Recent studies have reported that an accumulation of memory and terminally differentiated T cells in elderly subjects can fuel myocardial aging and boost the progression of heart diseases. Nevertheless, it...

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Bibliographic Details
Main Authors: Murilo Delgobo, Margarete Heinrichs, Nils Hapke, DiyaaElDin Ashour, Marc Appel, Mugdha Srivastava, Tobias Heckel, Ioakim Spyridopoulos, Ulrich Hofmann, Stefan Frantz, Gustavo Campos Ramos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
CD4+ T-cells
myocardial aging
inflammaging
NSG animals
immunosenescence
lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.584538/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.584538/full

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