A study of 82 extended HLA haplotypes in <it>HFE</it>-C282Y homozygous hemochromatosis subjects: relationship to the genetic control of CD8+ T-lymphocyte numbers and severity of iron overload

<p>Abstract</p> <p>Background</p> <p>It has been recently demonstrated that CD8+ T-lymphocyte numbers are genetically transmitted in association with the MHC class I region. The present study was designed with the objective of narrowing the region associated with the se...

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Bibliographic Details
Main Authors: Lacerda Rosa, Almeida Susana, Vieira Jorge, Cruz Eugénia, Gartner Andrea, Cardoso Carla S, Alves Helena, Porto Graça
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/7/16