The Ras GTPase-activating protein Rasal3 supports survival of naive T cells.

The Ras-mitogen-activated protein kinase (MAPK) pathway is crucial for T cell receptor (TCR) signaling in the development and function of T cells. The significance of various modulators of the Ras-MAPK pathway in T cells, however, remains to be fully understood. Ras-activating protein-like 3 (Rasal3...

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Bibliographic Details
Main Authors: Ryunosuke Muro, Takeshi Nitta, Toshiyuki Okada, Hitoshi Ideta, Takeshi Tsubata, Harumi Suzuki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368693?pdf=render